Publications
Select publications
- Tol MJ, Shimanaka Y, Tontonoz P, et al. "Dietary control of peripheral adipose storage capacity through membrane lipid remodelling." Nature Metabolism 2025 Jun 27. doi: 10.1038/s42255-025-01320-y. Epub ahead of print. PMID: 40579620. [Pubmed]
- Chan H, Li F, Gallo RL, et al. "Psychological stress increases skin infection through the action of TGFβ to suppress immune-acting fibroblasts." Science Immunology 2025 Apr 11;10(106):eads0519. doi: 10.1126/sciimmunol.ads0519. Epub 2025 Apr 11. PMID: 40215323; PMCID: PMC12183641. [Pubmed]
- Sammarco A, Guerra G, Badr CE, et al. "Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models." Communications Biology 2025 Apr 4;8(1):562. doi: 10.1038/s42003-025-07977-1. PMID: 40185889; PMCID: PMC11971295. [Pubmed]
- York AG, Skadow MH, Oh J, et al. "IL-10 constrains sphingolipid metabolism to limit inflammation." Nature 2024 Mar;627(8004):628-635. doi: 10.1038/s41586-024-07098-5. Epub 2024 Feb 21. PMID: 38383790; PMCID: PMC10954550. [Pubmed]
- Lee E, Williams KJ, McCarthy C, et al. "Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis." Journal of Lipid Research 2024 Feb;65(2):100496. doi: 10.1016/j.jlr.2024.100496. Epub 2024 Jan 6. PMID: 38185217; PMCID: PMC10844116. [Pubmed]
- Zhang S, Williams KJ, Verlande-Ferrero A, et al. "Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome." Journal of Lipid Research 2024 Feb;65(2):100434. doi: 10.1016/j.jlr.2023.100434. Epub 2023 Aug 26. PMID: 37640283; PMCID: PMC10839691. [Pubmed]
- Ferrari A, Whang E, Xiao X, et al. "Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake." Science 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966. Epub 2023 Nov 10. PMID: 37943936; PMCID: PMC11073449. [Pubmed]
- Hornburg D, Wu S, Moqri M, et al. "Dynamic lipidome alterations associated with human health, disease and ageing." Nature Metabolism 2023 Sep;5(9):1578-1594. doi: 10.1038/s42255-023-00880-1. Epub 2023 Sep 11. PMID: 37697054; PMCID: PMC10513930. [Pubmed]
- Almoughrabie S, Cau L, Cavagnero K, et al. "Commensal Cutibacterium acnes induce epidermal lipid synthesis important for skin barrier function." Science Advances 2023 Aug 18;9(33):eadg6262. doi: 10.1126/sciadv.adg6262. Epub 2023 Aug 18. PMID: 37595033; PMCID: PMC10438445. [Pubmed]
- Minami JK, Morrow D, Bayley NA, Fernandez EG, et al. "CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis." Cancer Cell 2023 Jun 12;41(6):1048-1060.e9. doi: 10.1016/j.ccell.2023.05.001. Epub 2023 May 25. PMID: 37236196; PMCID: PMC10330677. [Pubmed]
- Eyme KM, Sammarco A, Jha R, Mnatsakanyan H, et al. "Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse models." Science Translational Medicine 2023 Jan 18;15(679):eabq6288. doi: 10.1126/scitranslmed.abq6288. Epub 2023 Jan 18. PMID: 36652537; PMCID: PMC9942236. [Pubmed]
- Magtanong L, Mueller GD, Williams KJ, et al. "Context-dependent regulation of ferroptosis sensitivity." Cell Chemical Biology 2022 Oct 20;29(10):1568. doi: 10.1016/j.chembiol.2022.08.008. Erratum for: Cell Chem Biol. 2022 Sep 15;29(9):1409-1418.e6. doi: 10.1016/j.chembiol.2022.06.004. PMID: 36270234. [Pubmed]
- Ghorasaini M, Mohammed Y, Adamski J, et al. "Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring." Analytical Chemistry 2021 Dec 14;93(49):16369-16378. doi: 10.1021/acs.analchem.1c02826. Epub 2021 Dec 3. PMID: 34859676; PMCID: PMC8674878. [Pubmed]
- Flores YN, Amoon AT, Su B, et al. "Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico." Lipids Health and Disease 2021 Oct 10;20(1):136. doi: 10.1186/s12944-021-01526-5. PMID: 34629052; PMCID: PMC8504048. [Pubmed]
- Su B, Bettcher LF, Hsieh WY, et al. "A DMS Shotgun Lipidomics Workflow Application to Facilitate High-Throughput, Comprehensive Lipidomics." Journal of American Society of Mass Spectrometry 2021;10.1021/jasms.1c00203. doi:10.1021/jasms.1c00203. [Pubmed]
- Flores YN, Amoon AT, Su B, et al. "Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico." Lipids in Health and Disease 2021;20(1):136. Published 2021 Oct 10. doi:10.1186/s12944-021-01526-5. [Pubmed]
- Salisbury DA, Casero D, Zhang Z, et al. "Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits." Nature Metabolism 2021;3(7):940-953. doi:10.1038/s42255-021-00427-2. [Pubmed]
- Clifford BL, Sedgeman LR, Williams KJ, et al. "FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption." Cell Metabolism 2021;33(8):1671-1684.e4. doi:10.1016/j.cmet.2021.06.012. [Pubmed]
- Anastasia I, Ilacqua N, Raimondi A, et al. "Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis." Cell Reports 2021;34(11):108873. doi:10.1016/j.celrep.2021.108873. [Pubmed]
- Middlekauff HR, William KJ, Su B, et al. "Changes in lipid composition associated with electronic cigarette use." Journal of Translational Medicine 2020;18(1):379. Published 2020 Oct 7. doi:10.1186/s12967-020-02557-9. [Pubmed]
- Hsieh WY, Zhou QD, York AG, et al. "Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome." Cell Metabolism 2020;32(1):128-143.e5. doi:10.1016/j.cmet.2020.05.003. [Pubmed]
- Zhou QD, Chi X, Lee MS, et al. "Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins." Nature Immunology 2020;21(7):746-755. doi:10.1038/s41590-020-0695-4. [Pubmed]
- Williams KJ, Bensinger SJ. "Cellular Fatty Acid Analysis in Macrophage Using Stable Isotope Labeling." Methods in Molecular Biology 2020;2184:47-60. doi:10.1007/978-1-0716-0802-9_4. [Pubmed]
- Zhang Z, Feng AC, Salisbury D, et al. "Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice." Nature Communications 2020;11(1):984. 2020 Feb 20. doi:10.1038/s41467-020-14711-4. [Pubmed]
- Hsieh WY, Williams KJ, Su B, et al. "Profiling of mouse macrophage lipidome using direct infusion shotgun mass spectrometry." Star Protocols 2020 Dec 19;2(1):100235. doi:10.1016/j.xpro.2020.100235. [Pubmed]
- Leung KL, Sanchita S, Pham CT, et al. "Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal-weight polycystic ovary syndrome (PCOS) women during adipogenesis: evidence of cellular programming." Clinical Epigenetics 2020 Nov 23;12(1):181. doi:10.1186/s13148-020-00970-x. [Pubmed]
- Argus JP, Wilks MQ, Zhou QD, et al. "Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling." Cell Reports 2018;25(10):2919-2934.e8. doi:10.1016/j.celrep.2018.11.041. [Pubmed]